e-mail address: [email protected]
Position: Postdoctoral Research Associate
Education: Ph.D., University of Notre Dame
Research Interests: Molecular mechanisms governing tumor cell metastasis and ovarian cancer progression.
Book Chapters and Invited Reviews
 Yang, J., and Wang, S. (2013). Cancer gene therapy potential of neural stem cells derived from human embryonic stem cells and induced pluripotent stem cells. In Stem Cells and Cancer Stem Cells: Therapeutic Applications in Disease and Injury (Springer), Submitted.
Refereed Journal Articles
 Chen, C., Wang, Y., Goh, S. S., Yang, J., Lam, D. H., Choudhury, Y., Tay, F. C., Du, S., Tan, W. K., Purwanti, Y. I., Fan, W., and Wang, S. (2013). Inhibition of neuronal nitric oxide synthase activity promotes migration of human-induced pluripotent stem cell-derived neural stem cells toward cancer cells. J Neurochem. doi: 10.1111/jnc.12199.
 Yang, J., Lam, D. H., Goh, S. S., Lee, E. X., Zhao, Y., Tay, F. C., Chen, C., Du, S., Balasundaram, G., Shahbazi, M., Tham, C.K., Ng, W.H., Toh, H.C., and Wang, S. (2012). Tumor tropism of intravenously injected human-induced pluripotent stem cell-derived neural stem cells and their gene therapy application in a metastatic breast cancer model. Stem Cells 30, 1021-1029.
 Zhao, Y., Lam, D. H., Yang, J., Lin, J., Tham, C. K., Ng, W. H., and Wang, S. (2012). Targeted suicide gene therapy for glioma using human embryonic stem cell-derived neural stem cells genetically modified by baculoviral vectors. Gene Ther 19, 189-200.
 Lee, E. X., Lam, D. H., Wu, C., Yang, J., Tham, C. K., Ng, W. H., and Wang, S. (2011). Glioma gene therapy using induced pluripotent stem cell derived neural stem cells. Mol Pharm 8, 1515-1524.
 Ramachandra, C. J., Shahbazi, M., Kwang, T. W., Choudhury, Y., Bak, X. Y., Yang, J., and Wang, S. (2011). Efficient recombinase-mediated cassette exchange at the AAVS1 locus in human embryonic stem cells using baculoviral vectors. Nucleic Acids Res 39, e107.
 Guo, H., Choudhury, Y., Yang, J., Chen, C., Tay, F. C., Lim, T. M., and Wang, S. (2011). Antiglioma effects of combined use of a baculovirual vector expressing wild-type p53 and sodium butyrate. J Gene Med 13, 26-36.
 Yang, Y., Lo, S. L., Yang, J., Goh, S. S., Wu, C., Feng, S. S., and Wang, S. (2009). Polyethylenimine coating to produce serum-resistant baculoviral vectors for in vivo gene delivery. Biomaterials 30, 5767-5774.
 Yang, J., and O’Tousa, J. E. (2007). Cellular sites of Drosophila NinaB and NinaD activity in vitamin A metabolism. Mol Cell Neurosci 35, 49-56.
 Gu, G., Yang, J.1, Mitchell, K. A., and O’Tousa, J. E. (2004). Drosophila ninaB and ninaD act outside of retina to produce rhodopsin chromophore. J Biol Chem 279, 18608-18613.
 Yang, J., Ng, P. and Wang, S. (2008). Development of a rapid and accurate baculovirus titration method using quantitative real-time PCR, 9th Frontier Science Symposium, Singapore.
 Yang, J., and O’Tousa, J. E. (2005). Characterization of the Drosophila ninaB and ninaD genes involved in rhodopsin chromophore biosynthesis, A. Dros. Res. Conf. 46:691A, 46th Annual Drosophila Research Conference, San Diego.
 Yang, J., Gu, G., Mitchell, K.A. and O’Tousa, J. E. (2004). Drosophila ninaB and ninaD act outside of retina to produce rhodopsin chromophore, A. Dros. Res. Conf. 45:708C, 45th Annual Drosophila Research Conference, Washington D.C.
 O’Tousa, J. E., Gu, G., Sarfare, S. and Yang, J. (2003) The roles of ninaB, ninaD, and ninaG in rhodopsin maturation, Neurobiology of Drosophila, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 6/24/2013
1 Contribution equally as the first author.