e-mail address: [email protected]
Position: Postdoctoral Research Associate
Education: Ph.D., University of Notre Dame
Research Interests: Molecular mechanisms governing tumor cell metastasis and ovarian cancer progression.
Publications
Book Chapters and Invited Reviews
[1] Yang, J., and Wang, S. (2013). Cancer gene therapy potential of neural stem cells derived from human embryonic stem cells and induced pluripotent stem cells. In Stem Cells and Cancer Stem Cells: Therapeutic Applications in Disease and Injury (Springer), Submitted.
Refereed Journal Articles
[1] Chen, C., Wang, Y., Goh, S. S., Yang, J., Lam, D. H., Choudhury, Y., Tay, F. C., Du, S., Tan, W. K., Purwanti, Y. I., Fan, W., and Wang, S. (2013). Inhibition of neuronal nitric oxide synthase activity promotes migration of human-induced pluripotent stem cell-derived neural stem cells toward cancer cells. J Neurochem. doi: 10.1111/jnc.12199.
[2] Yang, J., Lam, D. H., Goh, S. S., Lee, E. X., Zhao, Y., Tay, F. C., Chen, C., Du, S., Balasundaram, G., Shahbazi, M., Tham, C.K., Ng, W.H., Toh, H.C., and Wang, S. (2012). Tumor tropism of intravenously injected human-induced pluripotent stem cell-derived neural stem cells and their gene therapy application in a metastatic breast cancer model. Stem Cells 30, 1021-1029.
[3] Zhao, Y., Lam, D. H., Yang, J., Lin, J., Tham, C. K., Ng, W. H., and Wang, S. (2012). Targeted suicide gene therapy for glioma using human embryonic stem cell-derived neural stem cells genetically modified by baculoviral vectors. Gene Ther 19, 189-200.
[4] Lee, E. X., Lam, D. H., Wu, C., Yang, J., Tham, C. K., Ng, W. H., and Wang, S. (2011). Glioma gene therapy using induced pluripotent stem cell derived neural stem cells. Mol Pharm 8, 1515-1524.
[5] Ramachandra, C. J., Shahbazi, M., Kwang, T. W., Choudhury, Y., Bak, X. Y., Yang, J., and Wang, S. (2011). Efficient recombinase-mediated cassette exchange at the AAVS1 locus in human embryonic stem cells using baculoviral vectors. Nucleic Acids Res 39, e107.
[6] Guo, H., Choudhury, Y., Yang, J., Chen, C., Tay, F. C., Lim, T. M., and Wang, S. (2011). Antiglioma effects of combined use of a baculovirual vector expressing wild-type p53 and sodium butyrate. J Gene Med 13, 26-36.
[7] Yang, Y., Lo, S. L., Yang, J., Goh, S. S., Wu, C., Feng, S. S., and Wang, S. (2009). Polyethylenimine coating to produce serum-resistant baculoviral vectors for in vivo gene delivery. Biomaterials 30, 5767-5774.
[8] Yang, J., and O’Tousa, J. E. (2007). Cellular sites of Drosophila NinaB and NinaD activity in vitamin A metabolism. Mol Cell Neurosci 35, 49-56.
[9] Gu, G., Yang, J.1, Mitchell, K. A., and O’Tousa, J. E. (2004). Drosophila ninaB and ninaD act outside of retina to produce rhodopsin chromophore. J Biol Chem 279, 18608-18613.
Conference Proceedings
[1] Yang, J., Ng, P. and Wang, S. (2008). Development of a rapid and accurate baculovirus titration method using quantitative real-time PCR, 9th Frontier Science Symposium, Singapore.
[2] Yang, J., and O’Tousa, J. E. (2005). Characterization of the Drosophila ninaB and ninaD genes involved in rhodopsin chromophore biosynthesis, A. Dros. Res. Conf. 46:691A, 46th Annual Drosophila Research Conference, San Diego.
[3] Yang, J., Gu, G., Mitchell, K.A. and O’Tousa, J. E. (2004). Drosophila ninaB and ninaD act outside of retina to produce rhodopsin chromophore, A. Dros. Res. Conf. 45:708C, 45th Annual Drosophila Research Conference, Washington D.C.
[4] O’Tousa, J. E., Gu, G., Sarfare, S. and Yang, J. (2003) The roles of ninaB, ninaD, and ninaG in rhodopsin maturation, Neurobiology of Drosophila, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 6/24/2013
1 Contribution equally as the first author.